Glaxon - Cheat - Lucy Ellis

Glaxon - Cheat - Lucy Ellis

You can’t out train a bad diet.
Blah blah blah.


Well, in some respects this is true. But, sometimes that naughty food is too tempting, or it is simply the only way that you can increase your calorie intake!


Carbohydates make up for a huge portion of our diet and more so when we utiise them for exercise purposes. They give us energy, give our muscles fullness and a “pump” and are the primary source of fuel for the brain. Carbs are broken down into glycogen and the body does one of two things with them:

1. Send them to the muscles to be used as energy.
2. Send them for storage for a later use.

The ingredients within Cheat have been used as traidiontal medicinal herbs. These hypoglycemic herbs can help to:

- Increase insulin secretion
- Enhance glucose uptake by adipose (fat) or muscle tissues
- Inhibit glucose absorption from intestine
- Inhibit glucose production from the liver

The main ingredient within Cheat is Chromium.

Chromium is a trace element which is present in many foods such as meats and vegetables – your Sunday lunch basically. But soil, agricultural and manufacturing processes vary the amount of chromium present, therefore it is mostly available as a supplement. It has been extensively studies for its role in regulating insulin levels following meals.

So how does this work? Well the precise mechanism has not been identified, but multiple studies have proposed that chromium binds to an oligopeptide to form a lower-molecular weight binding substance that binds and activates to the insulin receptor to promote insulin action. Further studies have also outlined its beneficial role in reducing oxidative stress, thereby acting as an antioxidant. has been extensively studied in helping to regulate insulin levels following a heavy carbohydrate meal. Chromium has been combined with cinnamon to increase this effect.

 

Berberine
Berberine is known to exert a hypoglycemic effect which just means that is reduces glucose. Its actions aren’t through expression of the glucose transporter 4 (GLUT4) or its gene expression, but in other methods of stimulating glucose uptake. Cellular models demonstrate increased signal transduction mediated by the PI3K-independent pathway which leads to glucose uptake.

PI3K pathway is a signalling pathway which has multiple implications on cellular metabolism. Interestingly, this same study reported increases in the low-density lipoprotein receptor via activation of ERK1/2 but not the Akt pathway. This is critical information because normally PI3K activates the AKt pathway as seen in the pretty picture below. Further cellular models identified long-lasting AMPK and p38-MAPK phosphorylation induced by berberine, which enhances glycolysis.


Important and saucy information as it identifies a useful method of improving glucose metabolism especially in type 2 diabetic individuals. But basically, what this information says, is that berberine exerts its hypoglycemic effect independent of insulin.



Bitter melon
Bitter melon, kind of looks like a spiky cucumber, but it has been used for centuries in traditional medicine for the treatment of diabetes. Bitter melon contains a unique balance of bioactive compounds such as flavonoids, isoflavones, glucosinolates or importantly, charatin, vicine and polypeptide-p which show significant insulin releasing activity in cell cultures. Its blood glucose lowering effects are attributed activation of PPAR-γ which helps to control energy balance.

Further, bitter melon has also been shown to protect pancreatic B-cells through downregulation of MAPKs and NF-kB which is useful in both anti-hyperglycemic (increased blood glucose) and hypoglycemic effects.

Maslinic Acid
Maslinic acid found in loquat, helps to enhance the insulin signalling pathway and inhibits glycogen phosphorylase which moves glucose quicker out of the
blood.

Corsolic Acid
Corsolic acid (found in banaba leaf) and pomegranate further stimulate glucose uptake by enhancing phosphorylation. A significant decrease (16.6%)

in fasting blood glucose levels was observed in individuals with fasting blood glucose levels greater than 110mg/dL.

After 6 months and 1-year, significant improvements in
glucose tolerance were observed following treatment with banaba extract. Importantly, banaba didn’t induce hypoglycaemia and no adverse effects were observed.

This GDA or Glucose Disposal agent means that carbohydrates you consume (and broken down) “go” to the right place. Refuel the muscles following a workout. Enhance insulin sensitivity following an off plan meal.


Now, this isn’t going to make you thin if you don’t follow your diet, but for those individuals who consume mass amounts of calories, a GDA can be useful.

The panel of ingredients look superior to many of the GDAs that we have seen before and the only way that you will know how it works, is to try it!

 

Lucy Ellis - Educator